Mark Sloan and Callie Torres

In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Callie and Mark have a conversation outside Seattle Grace. What's to come of their relationship, if anything?
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Torres and Sloan

In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Callie and Mark have a conversation outside Seattle Grace. What's to come of them?
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Mark and Callie

In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Callie and Mark share a moment outside the hospital. What's to come of these two?
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Patience with Patients

Meredith Grey monitors patients in this photo from the fourth season finale of Grey's Anatomy, "Freedom." She and Derek also must hash things out.
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Trials Continue

In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Meredith and Derek continue work on their clinical trial... and the trials of their own lives.
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Celebration?

In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Meredith is holding a bottle of what appears to be champagne. Think there's something to celebrate?
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Richard, Derek and Mark

In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Derek, Mark and Richard are seen in a rare scene outside Seattle Grace. Where is it?
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Grey, Meredith

In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Meredith Grey has some work to do... will this episode end with her and Derek together?
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That Derek Look

In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Derek gives Meredith that look he's known for. How can anyone possibly resist?
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Freedom

In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Meredith and Derek hash things out. Will Meredith achieve "freedom" from her demons?
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The MerDer Reunion

In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Meredith and Derek discuss their clinical trial... and figure out their lives. Hopefully.
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Izzie Gonna Listen?

In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Izzie is up in the face of Alex, ready to tell him how she feels. How will this end?
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Grey's Anatomy Season 4 Quotes

Everyday is my mothers birthday. My mother was born in March. He lied. He's a liar. And I'm glad. Really, I'm glad that you found him charming. I'm sure he was delightful. He's a blast after five drinks, not so much after nine though; he gets a little weepy and mean. He's a drunk, Meredith. He probably came in and told you how wonderful you are. How sad he is he doesn't get to spend more time with you. You know, yesterday he told me I was his favorite daughter. The day before, I was an ungrateful bitch. The week before, he wrote me a check for $20,000 because he said I deserved everything life had to offer, because he was so proud of me, a lifetime's worth of proud. So thank you for letting me know that I need to keep a better eye on him. Thanks.

Lexie

Meredith: I will take the ER and your interns.
Cristina: Are you sure?
Meredith: Take the surgery. Makes you feel better and you start to regain strength. [leaves]
Alex: I saw the whole thing, Yang. You can stop pretending.
Cristina: Oh I'm not pretending. I'm sad. I'm very sad. Me so sad!
Alex: Yes, you tried.
Cristina: Hey, forget it. Sad is mine. Go, find your own pretend-emotion.