A portrait of Patrick Dempsey, taken by Entertainment Weekly in October 2007. We love this handsome actor and millions of Grey's Anatomy fans agree.

Patrick Dempsey wearing a towel... not the way some fans might wish, but still, he looks great in this picture.

Patrick Dempsey out and about in Paris, France. The actor did some sight-seeing, even if it looks as if he's on a movie set!

Patrick Dempsey takes a stroll through Paris, France - on his own, not as part of a movie scene. Though he looks the part. As always, he's terrific.

Patrick Dempsey, who plays Derek Shepherd, smiles in a recent interview with Entertainment Tonight. He expressed great concern over the impending Hollywood writers' strike.

Patrick Dempsey in the movie poster for his 2007-2008 movie "Made of Honor." He's looking very McDreamy as always.

We love Patrick and Jillian Dempsey, and it's always nice to see the real-life Mrs. McDreamy out and about with her star husband. They have three children together.

Patrick Dempsey and his "Enchanted" co-star Amy Adams. Patrick is seen here at the film's premiere in November of 2007. He has said that he made the film in part because of his daughter, Talula.

Patrick Dempsey is all about the quiet life, settling down and raising his family. When his recent run on Grey's Anatomy ends, look for this actor to lay low for awhile.

Patrick Dempsey has his unique style and is never one to bow to conventions. Perhaps this is one of the reasons his fans are so devoted to him. Besides his talent and great looks, of course.

Dempsey takes to the bike with the writers' strike leaving him temporarily out of work. Oh well, more time for Patrick to spend with the wife and kids!

Patrick Dempsey was named Star of the Year by People in 2007. The Grey's Anatomy star certainly deserves the honor after great success on and off-screen.